LT Trent Williams
There may not have been a bigger offseason acquisition for the 49ers than Williams. They acquired the seven-time Pro Bowler shortly before long-time left tackle Joe Staley announced his retirement. Typically there wouldn’t be a lot of intrigue with a player who is widely considered one of the three or four best left tackles in the league. However, a holdout followed by the removal of a cancerous growth on his skull forced Williams to miss all of the 2019 campaign. He hasn’t played since the end of the 2018 season, so there’s no guarantee he steps back in at peak form. With one year left on his contract, Williams’ return to a Pro Bowl level has long-term ramifications for his career and a short-term impact on the success of the 49ers’ offense.