CB Pierre Desir

Obviously, this one only matters if Desir winds up playing—he’s currently listed as questionable with a groin injury. However, the Colts need to get better production out of their veteran cornerback after a year of inconsistent play.

Desir could very well be tasked with covering arguably the best wide receiver in the NFL: Michael Thomas. Currently leading the NFL in receptions (121) and receiving yards (1,424), Thomas is on the brink of making history if he continues his pace.

Desir won’t always be covering Thomas on Monday night but when he does, it will come with the near-impossible task of slowing him down. If Desir plays, he will hold a big role in the success of the passing defense.