LT Joe Staley
There’s no guarantee Staley plays. He’s officially listed as questionable. However, the necessity of getting the run game started and keeping Garoppolo clean apply to his side of the offensive line as well. Staley’s played in only three games this season due to injury, and his first return in Week 10 against Seattle didn’t go well. Staley wasn’t 100 percent coming off a broken fibula, and it showed. Three more weeks off to heal a surgically repaired fractured, dislocated finger should help Staley be more productive if he is in the lineup.