49ers defense gets another tough test vs. multi-faceted Saints offense

The 49ers defense has passed all of its tests this year, but Michael Thomas, Drew Brees and Alvin Kamara are a different type of challenge.

CB Richard Sherman

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Sherman hurt his knee late against Baltimore, but didn’t show up on the injury report this week after doing limited practice work. It’ll be interesting to see how the Saints attack the veteran and whether they line up Michael Thomas against him. Thomas is the most prolific receiver in the game, and Brees pretty rarely throws incompletions when targeting him. If Sherman wins that matchup, the Saints passing offense could struggle.