49ers defense gets another tough test vs. multi-faceted Saints offense

The 49ers defense has passed all of its tests this year, but Michael Thomas, Drew Brees and Alvin Kamara are a different type of challenge.

DE Nick Bosa

Cary Edmondson-USA TODAY Sports

Bosa’s been at his most effective against pocket passers like Drew Brees. If he can wreck the game Sunday and get the Saints out of rhythm on offense, he could singlehandedly spark the 49ers defense. Bosa may also get matched up against a backup left tackle with starter Terron Armstead still working through an ankle injury. Bosa’s taken advantage of those matchups this season, and a multi-sack game from him would be massive for the rookie.

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