49ers all-time record vs. 2020 opponents

The San Francisco 49ers have a tough slate of opponents on their 2020 schedule, but they’ve had some good success historically against them.

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New England Patriots: 8-5

San Francisco used to be 7-2 all-time against the Patriots, but the dominant New England machine has rattled off three wins in their last four matchups.

New Orleans Saints: 49-26-2

Getting to beat up on some bad Saints teams while they were part of the NFC West helped the 49ers inflate this record some. New Orleans has picked up some ground over the last 20 years though with 10 wins across their last 16 meetings.

New York Giants: 20-21

This is a lot like the Dolphins’ situation where the 49ers should be favored heavily to even up the all-time series.