The original run of The X-Files included 217 episodes over nine seasons, meaning there were a lot of opportunities for guest stars. Creator Chris Carter did not let those opportunities pass, often nabbing already big names for an extraterrestrial experience or turn with a creepy monster-of-the-week.
Filmed in Vancouver, British Columbia, there were also a lot of yet-discovered and soon-to-be huge stars, including a teenage Ryan Reynolds and a very young Lucy Liu.
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Let’s get into some of the biggest cameos and guest-starring roles, but please note this is by no means all-inclusive.