4 49ers players who could make an impact vs. Cardinals in wake of injuries

These players will play a more prominent role than normal because of injuries.

RB Tevin Coleman

Kirby Lee-USA TODAY Sports

With Matt Breida, the team’s leading rusher, unlikely to play, that leaves Coleman as the main back on offense. He is capable of having big games, as he had 105 rushing yards on only 11 carries against the Carolina Panthers.

Expect the Niners to give him the ball a lot.

[protected-iframe id=”e1d0fe3745adff805885f9c1789909c9-112738498-106269283″ info=”https://api.spreaker.com/v2/episodes/20006504/download.mp3″ ]