Looking to bet on College Football for the 2021-22 season? This page will track the odds to win the College Football Playoff National Championship throughout the season leading up to the Jan. 10 final at Lucas Oil Stadium in Indianapolis. Keep checking back to SportsbookWire.com for all of our weekly NCAAF odds, picks and predictions.
The 2021-22 College Football season begins with a five-game slate Saturday. The Week 0 matchups precede next week’s full schedule with games taking place Wednesday through Monday.
Alabama heads into the 2021-22 college football season as the favorite to win a second straight CFP National Championship. Head coach Nick Saban and ‘Bama have won three of the seven titles since the new format was introduced for the 2014-15 season. The Crimson Tide played in five of the seven championship games.
College Football Week 0 odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 9:50 a.m. ET
Nebraska at Illinois, 1 p.m. ET
Money line: Nebraska -280 (bet $280 to win $100) | Illinois +220 (bet $100 to win $220)
Against the spread (ATS): Nebraska -6.5 (-122) | Illinois +6.5 (-102)
Over/Under (O/U): 54.5 (O: -120 | U: -105)
UConn at Fresno State, 2 p.m. ET
Money line: UConn +1300 (bet $100 to win $1,300) | Fresno State -5000 (bet $5,000 to win $100)
Against the spread (ATS): UConn +27.5 (-110) | Fresno State -27.5 (-110)
Over/Under (O/U): 62.5 (O: -110 | U: -110)
Hawaii at UCLA, 3:30 p.m. ET
Money line: Hawaii +470 (bet $100 to win $470) | UCLA -700 (bet $700 to win $100)
Against the spread (ATS): Hawaii +17.5 (-115) | UCLA -17.5 (-107)
Over/Under (O/U): 68.5 (O: -108 | U: -112)
UTEP at New Mexico State, 9:30 p.m. ET
Money line: UTEP -333 (bet $333 to win $100) | New Mexico State +260 (bet $100 to win $260)
Against the spread (ATS): UTEP -8.5 (-110) | New Mexico State +8.5 (-110)
Over/Under (O/U): 54.5 (O: -108 | U: -112)
Southern Utah at San Jose State, 10 p.m. ET
Money line: Off the board (OTB)
Against the spread (ATS): OTB
Over/Under (O/U): OTB
Check back for odds on this game.
2022 College Football Playoff National Championship odds
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday, Aug. 23.
| Team | CFP National Championship Odds | Bet $100 to win |
| Alabama | +250 | $250 |
| Clemson | +350 | $350 |
| Ohio State | +550 | $550 |
| Georgia | +550 | $550 |
| Oklahoma | +800 | $800 |
| LSU | +3000 | $3,000 |
| Texas A&M | +3000 | $3,000 |
| Iowa State | +3000 | $3,000 |
| Florida | +4000 | $4,000 |
| North Carolina | +5000 | $5,000 |
| USC | +5000 | $5,000 |
| Oregon | +5000 | $5,000 |
| Wisconsin | +6000 | $6,000 |
| Miami | +7000 | $7,000 |
| Notre Dame | +7000 | $7,000 |
| Penn State | +8000 | $8,000 |
| Cincinnati | +9000 | $9,000 |
| Indiana | +9000 | $9,000 |
| Oklahoma State | +10000 | $10,000 |
| Michigan | +10000 | $10,000 |
| Auburn | +10000 | $10,000 |
| Washington | +10000 | $10,000 |
| Arizona State | +10000 | $10,000 |
| Nebraska | +20000 | $20,000 |
| West Virginia | +20000 | $20,000 |
| Texas | +20000 | $20,000 |
| Tennessee | +20000 | $20,000 |
| Kentucky | +20000 | $20,000 |
When is the 2022 CFP National Championship?
Monday, Jan. 10; kickoff will be at 8 p.m. ET
Where is the 2022 CFP National Championship?
Lucas Oil Stadium, Indianapolis
How to watch the 2022 CFP National Championship
Watch the 2022 College Football Playoff National Championship on ESPN
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