There are a bunch of teams in the NFL right now that have a legitimate chance to win the Super Bowl. However, the team that wins the most games in the regular season isn’t always the last one standing in February. Below, we look at the odds of which team will win the most games during the 2021 season, with NFL picks, predictions and best bets.
The favorites to win the most games this season are fairly obvious. It’s the same teams most people expect to contend for a championship, with a fairly even split between the AFC and NFC. The Kansas City Chiefs and Tampa Bay Buccaneers are atop the heap after playing in Super Bowl LV, while the Buffalo Bills continue to garner respect as a legitimate threat in the AFC.
The Los Angeles Rams and San Francisco 49ers are tied for the same odds to lead the league in wins this season, with the Seattle Seahawks not far behind – a testament to the competitiveness in the NFC West. But who are the best bets when weighing which team could finish with the most wins?
Also see: Which team will win the fewest games in 2021?
Picks to win the most games in 2021
Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Aug. 26.
Kansas City Chiefs (+450)
The Chiefs led the league with a 14-2 record last season, one game better than the Bills and Green Bay Packers. So it’s no surprise they’re the favorites to once again finish with the most wins.
Considering they’ve won at least 10 games in seven of their eight years under head coach Andy Reid and in each of the last six seasons, they’re a good bet to win the most games in 2021. With QB Patrick Mahomes, WR Tyreek Hill, TE Travis Kelce and an underrated defense led by FS Tyrann Mathieu, the Chiefs look like the best team in the league once again.
The only thing working against them is that the AFC West will be tougher now that the Los Angeles Chargers and Las Vegas Raiders look like formidable foes.
Tampa Bay Buccaneers (+600)
The defending Super Bowl champs returned every starter on offense and defense. QB Tom Brady also continues to play at a high level, so it’s no wonder the Bucs seem ready to repeat. They won 11 games last season before going on a run in the playoffs, really finding their groove in Week 14 when their eight-game winning streak began.
After an up-and-down first 12 games of the season, the Buccaneers found a rhythm when it mattered most.
It’s scary to think about what they could do if they get off to a hot start in 2021. They have winnable games against the Atlanta Falcons, New England Patriots, Miami Dolphins, Philadelphia Eagles, Chicago Bears and New Orleans Saints in the first half, too, before facing the New York Giants, New York Jets and Carolina Panthers in the second half.
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Green Bay Packers (+1000)
Everything clicked for the Packers on offense last season. QB Aaron Rodgers was the NFL MVP, RB Aaron Jones broke out in a big way and WR Davante Adams was an All-Pro. The defense was decent, too, ranking ninth in yards allowed. The result was a 13-3 finish.
They have most of the band back together this season and play in a fairly soft division where the Minnesota Vikings, Bears and Detroit Lions are all expected to fight for a wild-card spot at best. The Packers are a great value to lead the league in wins at +1000 with a schedule that isn’t too daunting.
Los Angeles Rams: (+1200)
The Rams have a new look with QB Matthew Stafford under center after a blockbuster trade with the Lions this offseason. That move alone makes them Super Bowl contenders, but there are some hurdles, too. RB Cam Akers is out for the year, they suffered major losses in free agency and Brandon Staley is no longer the defensive coordinator.
The schedule is also no cakewalk in the NFC West, but if the defense continues its reign as the top unit in the NFL and the offense takes even a marginal step forward with Stafford, the Rams will threaten to win 13-14 games.
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Long shot: Tennessee Titans (+3000)
The Titans were somewhat underrated last season as an 11-5 team, but they should be taken seriously in 2021. The Jacksonville Jaguars aren’t going to be very good, the Indianapolis Colts have quarterback questions with Carson Wentz and the Houston Texans might be the worst team in the league.
That’s six fairly favorable games for the Titans, though their other out-of-division matchups feature the Arizona Cardinals, Seahawks, Rams, Pittsburgh Steelers, 49ers, Chiefs and Bills.
However, at +3000, the Titans look like a great value to potentially have a great season. An offense that features RB Derrick Henry, WR Julio Jones and WR A.J. Brown should not be overlooked.
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