South Carolina at Clemson odds, picks and predictions

Analyzing Saturday’s South Carolina at Clemson odds and lines, with college football expert picks, predictions and best bets.

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The No. 14 South Carolina Gamecocks (8-3) and the No. 12 Clemson Tigers (9-2) meet at Memorial Stadium Saturday. Kickoff is slated for noon ET (ESPN). Below, we look at South Carolina vs. Clemson odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

South Carolina secured its fifth consecutive win with a commanding 56-12 triumph over Wofford Nov. 23. The Gamecocks amassed 608 total yards, including 343 through the air and 265 on the ground. QB LaNorris Sellers threw for 307 yards with 3 TDs and 1 INT while rushing for 53 yards and a score. On defense, South Carolina dominated, holding Wofford to a mere 28 rushing yards while stifling any offensive rhythm from the Terriers.

Clemson earned its third consecutive victory, cruising past the Citadel Bulldogs 51-14 Nov. 23. QB Cade Klubnik tossed for 198 yards with 3 TDs, while RB Jay Haynes rushed for 118 yards and 2 scores. WR Antonio Williams contributed 5 catches for 72 yards and 2 TDs. Despite the dominant win, the Tigers struggled defensively, allowing 288 rushing yards to the Bulldogs.

– RankingsUS LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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South Carolina at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 2:50 p.m. ET.

  • Moneyline (ML): South Carolina +125 (bet $100 to win $125) | Clemson -150 (bet $150 to win $100)
  • Against the spread (ATS): South Carolina +3 (-110) | Clemson -3 (-110)
  • Over/Under (O/U): 49.5 (O: -105 | U: -115)

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South Carolina at Clemson picks and predictions

Prediction

South Carolina 24, Clemson 21

Moneyline

BET SOUTH CAROLINA (+125).

The Gamecocks have one of their strongest teams in recent years, as well as the potential to win this game on the road.

Clemson is 1-4 ATS in its last 5 games, while South Carolina has covered 5 of its last 6.

The Gamecocks come into this matchup riding a 5-game winning streak, showing strong momentum and the ability to perform when it matters. South Carolina’s defense has been outstanding, ranking 12th in FBS in scoring defense (18.8 points allowed per game) and 19th against the run, allowing just 110.9 yards per game.

This will be crucial against a Clemson team that relies on its running game with Klubnik and RB Phil Mafah. The Gamecocks’ defense is well-equipped to slow down Clemson’s ground game and force it into more predictable situations.

On offense, South Carolina has a balanced attack with a solid rushing game, ranked 4th in the SEC, led by RB Raheim “Rocket” Sanders with 821 yards and 11 TDs. Sellers has also been efficient and is ranked 25th nationally in passer rating. South Carolina’s versatility presents challenges for Clemson’s defense, which has had occasional struggles.

Against the spread

PASS.

I’m all about getting those plus odds on the moneyline, but if you want to play it safe and take the field goal, I won’t fault you.

Over/Under

BET UNDER 49.5 (-115).

Clemson’s offense has been inconsistent, despite ranking 11th in scoring offense (36.3 points per game). While it has faced weaker defenses, South Carolina’s defense should be more effective at limiting big plays. Clemson has hit the Under in 6 of its last 8 games.

Both teams favor a slow, methodical style of play, relying on defense and ball control rather than high-scoring affairs. South Carolina’s strong run game complements its defense.

With both teams focused on avoiding mistakes in a high-stakes matchup, this game is likely to stay under the total. Expect a typical SEC-ACC showdown, marked by defensive battles and a clock-controlling approach. Take the Under for this one.

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