First look: South Carolina at Clemson odds and lines

Looking at Saturday’s South Carolina at Clemson college football odds, lines and trends. Here’s what you need to know.

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The No. 14 South Carolina Gamecocks (8-3) and the No. 12 Clemson Tigers (9-2) meet at Memorial Stadium Saturday. Kickoff is slated for noon ET (ABC). Below, we look at South Carolina vs. Clemson odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

South Carolina extended their winning streak to 5 games with a dominant 56-12 victory over the Wofford Terriers. The Gamecocks racked up 608 total yards (343 passing and 265 rushing). QB LaNorris Sellers passed for 307 yards, 3 TDs and 1 INT, while also rushing for 53 yards and a score. The defense was stout, limiting Wofford to just 33 rushing yards.

Clemson secured its third straight win, dominating the Citadel Bulldogs 51-14. QB Cade Klubnik threw for 198 yards and 3 TDs, RB Jay Haynes rushed for 118 yards and 2 TDs and WR Antonio Williams had 5 receptions for 72 yards and 2 scores. Despite the lopsided victory, the Tigers gave up 288 rushing yards to the Bulldogs.

– RankingsUS LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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South Carolina at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 10:42 a.m. ET.

  • Moneyline (ML): South Carolina +115 (bet $100 to win $115) | Clemson -135 (bet $135 to win $100)
  • Against the spread (ATS): South Carolina +2.5 (-105) | Clemson -2.5 (-115)
  • Over/Under (O/U): 49.5 (O: -105 | U: -115)

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2024 betting stats

  • ML: South Carolina 8-3 | Clemson 9-2
  • ATS: South Carolina 8-3 | Clemson 5-5
  • O/U: South Carolina 7-4 | Clemson 3-7

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South Carolina vs. Clemson head-to-head

Clemson leads the all-time series 73-43-4, winning 8 of the last 9 matchups. Last Nov. 25 the Tigers won 16-7 in Columbia, covering as a 7.5-point road favorite with the Under 48 hitting.

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