San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (71-59) and San Francisco Giants (61-66) meet Tuesday at 9:45 p.m. ET to continue a 3-game series at Oracle Park. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

Season series: San Diego leads 9-5

San Diego has had its share of woes on the road. The Padres are 12-20 away from home since June 17. However, San Diego is 3-1 with an .894 OPS on its current road trip after a 6-5 win over the Giants Monday.

The Giants have lost 5 straight games, and their pitching has been beaten up in the process. San Francisco owns a bloated 6.59 ERA over that span. The Giants have gone 10-15 with a 4.62 ERA in August.

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Padres at Giants projected starters

LHP Blake Snell vs. RHP Logan Webb

Snell (5-7, 4.24 ERA) has made 17 starts this season. He has a 1.34 WHIP, 3.9 BB/9 and 12.0 K/9 through 87 IP.

  • Has been hurt by a .330 batting average on balls in play.
  • Has faced the Giants twice this season and yielded just 2 ER in 11 2/3 IP.
  • Current San Francisco batters own an aggregate .543 OPS against him.

Webb (11-7, 3.33 ERA) owns a 1.19 WHIP, 2.5 BB/9 and 7.3 K/9 through 159 1/3 IP across 26 starts.

  • Allowed 6 runs over 4 2/3 IP at the Detroit Tigers in his last start and has registered a 4.75 ERA in his last 7 outings.
  • Has faced San Diego twice this season and allowed 2 ER in 16 IP.
  • Owns a nifty 2.94 ERA at home over the last 3 seasons (2020-22).

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:51 p.m. ET.

  • Money line: Padres -125 (bet $125 to win $100) | Giants +102 (bet $100 to win $102)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+135) | Giants +1.5 (-170)
  • Over/Under (O/U): 7.5 (O: +100 | U: -125)

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Padres at Giants picks and predictions

Prediction

Padres 4, Giants 3

Money line

Snell has allowed 1 or 0 runs in 5 of his last 7 starts. The San Francisco offense is prone to long batting slumps and may be in one now.

TAKE SAN DIEGO (-125).

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Run line/Against the spread

The Friars have the better bullpen, but the back end of that ‘pen is caution-flag fatigue territory. It’d be wise to AVOID the run line in taking the road favorite with a low total.

Over/Under

Both starters have good numbers against the batters they’ll see tonight. The Under 7.5 is the play … but only up to -120. PASS otherwise.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Monday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (70-59) and San Francisco Giants (61-65) meet Monday night at 9:45 p.m. ET to launch a 3-game series at Oracle Park. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

Season series: San Diego leads 8-5

The Padres are continuing a trip that opened with the club taking 2 of 3 games at the Kansas City Royals over the weekend. San Diego has had its share of woes on the road. The Padres are 11-20 away from home since June 17.

The Giants are back at home after a shaky 2-6 road trip that saw them bat all of .190/.274/.299 (.572 OPS). San Francisco has scuffled its way to a 13-22 mark in the second half.

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Padres at Giants projected starters

RHP Mike Clevinger vs. LHP Carlos Rodon

Clevinger (4-5, 3.59 ERA) has made 15 starts and 1 relief appearance. He has posted a 1.16 WHIP, 2.9 BB/9 and 7.8 K/9 through 80 1/3 IP.

  • Has battled control problems of late with 9 walks across his last 15 1/3 IP over 3 starts.
  • Has walked 3.3 batters per 9 innings while notching a 4.02 road ERA.

Rodon (12-6, 2.81 ERA) has authored a 1.03 WHIP, 2.5 BB/9 and 11.5 K/9 through 147 1/3 IP across 25 starts.

  • Owns a 1.80 ERA in 2 starts against San Diego this year.
  • Coming off allowing 1 run over 7 IP against the Detroit Tigers Tuesday. Has held opponents to 1 or 0 runs in 6 of his last 9 starts.
  • Has clocked a 1.86 ERA at home (1.25 ERA since June 12).

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:09 p.m. ET.

  • Money line: Padres +105 (bet $100 to win $105) | Giants -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-205) | Giants -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: +100 | U: -125)

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Padres at Giants picks and predictions

Prediction

Giants 5, Padres 3

Money line

Peg Mike Clevinger as being too far out over his skis with his surface line. Clevinger has benefited from a .249 batting average on balls in play and he’s been fortunate with a high left-on base rate also.

The Giants are just 4 for their last 35 (.114 BA) with runners in scoring position.

Look for a bounce-back: take the GIANTS (-130).

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Run line/Against the spread

Both teams tend to play more 1-run games than the average club, so there is some risk on this GIANTS -1.5 (+165) play. However, the price is attractive so some bettors may want to include this play in a smaller dose alongside the above ML.

Over/Under

These offenses both have an Under lean, but before unleashing a play, it’d be best to find a game where both starters do also. That’s not the case here with a suspect Clevinger line.

AVOID.

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Sunday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (26-14) and San Francisco Giants (22-17) meet Sunday at 4:05 p.m. ET for the finale of a 3-game series at Oracle Park. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

Season series: Padres lead 3-2.

The Padres have won the first 2 games of this series, both in 1-run fashion. San Diego heads into this Sunday matinee having won 5 of its last 6 contests.

Friday’s game snapped a 5-game home win streak for the Giants. San Francisco pitching was on fire early in the season with a 2.32 ERA through April 27 but has logged a 5.47 mark since.

Padres at Giants projected starters

LHP MacKenzie Gore vs. LHP Alex Wood

Gore (2-1, 2.17 ERA) — a rookie — owns a 1.21 WHIP, 2.8 BB/9 and 9.9 K/9 through 29 IP in 5 starts and 1 relief appearance.

  • Has tossed between 5-5 2/3 IP in each of his 5 starts.
  • Allowed 3 runs on 7 hits across 5 IP in his last start against the Chicago Cubs May 9.
  • Tossed 3 scoreless innings in long relief Tuesday at the Philadelphia Phillies.

Wood (3-2, 3.93 ERA) has logged a 1.40 WHIP, 2.6 BB/9 and 9.2 K/9 through 34 1/3 IP across 7 starts.

  • Allowed 3 R on 6 H in 4 1/3 IP in his last start Monday at the Colorado Rockies.
  • Has held Padres batters to an aggregate .588 OPS in a small sample of 59 plate appearances.

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 9:20 a.m. ET.

  • Money line: Padres +120 (bet $100 to win $120) | Giants -145 (bet $145 to win $100)
  • Run line (RL): Padres +1.5 (-180) | Giants -1.5 (+145)
  • Over/Under (O/U): 7.5 (O: -112 | U: -108)

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Padres at Giants picks and predictions

Prediction

Giants 4, Padres 2

Money line

The Friars are 9-4 in 1-run games and have an overall record outkicking the coverage of 4.38 runs per game vs. 3.88 RPG allowed. San Diego has the better relief corps in a vacuum, but after a couple close games, the back end of that group will be held in check Sunday.

San Francisco is the play at -135 or better. PASS otherwise.

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Run line/Against the spread

An outward breeze out is expected in the forecast. That’s less of a concern for Wood than Gore. The veteran Giants hurler gets more ground balls.

With a solid Under, a ML play — at a better price — would be more advisable. But at current prices, some bettors may want to hold their noses and go with SAN FRANCISCO -1.5 (+145).

Over/Under

Both offenses have some quality-of-contact figures that point to their surface numbers being a bit overcooked. With Wood starting for the Giants, THE UNDER 7.5 (-108) HAS VALUE.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Saturday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (25-14) and San Francisco Giants (22-16) meet Saturday at 4:10 p.m. ET in the continuation of a 3-game series at Oracle Park. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

Season series: tied 2-2.

The Padres won Friday’s series opener 8-7 in 10 innings. San Diego heads into this Saturday matinee having won 4 of its last 5.

Friday’s game snapped a 5-game home win streak for the Giants. San Francisco pitching was on fire early in the season with a 2.32 ERA through April 27 but has logged a 5.66 mark since.

Padres at Giants projected starters

RHP Joe Musgrove vs. LHP Carlos Rodon

Musgrove (4-0, 2.20 ERA) has logged a 0.93 WHIP, 1.2 BB/9 and 9.4 K/9 through 45 IP across 7 starts.

  • Clocked a 6.08 ERA while allowing an .898 OPS in 5 starts vs. San Francisco last season.
  • Averages 92 pitchers per start but has made 108 and 99 over his last 2 turns.

Rodon (4-2, 3.49 ERA) is tabbed for his 8th start. He has a 1.11 WHIP, 3.0 BB/9 and 13.0 K/9 through 38 2/3 IP.

  • Toted a 1.80 ERA into his last start but allowed 8 runs on 10 hits in 3 2/3 IP vs. the St. Louis Cardinals Sunday.
  • Owns a 2.12 ERA and 1.06 WHIP in 17 IP at home.

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:11 a.m. ET.

  • Money line: Padres +115 (bet $100 to win $115) | Giants -140 (bet $140 to win $100)
  • Run line (RL): Padres +1.5 (-190) | Giants -1.5 (+155)
  • Over/Under (O/U): 6.5 (O: -125 | U: +100)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Padres at Giants picks and predictions

Prediction

Giants 4, Padres 2

Money line

Expect a bounce-back for Rodon after a couple of high-pitch efforts likely led to the rocky outing in his last turn. His overall numbers have some play because he’s pitched through a .345 batting average on balls in play.

The Giants’ 5.16 runs per game rank second in MLB, and the home nine has had its way in games against Musgrove. S.F. has been okay versus righties so far, but that’s with a .248 BABIP.

Take SAN FRANCISCO (-140).

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Run line/Against the spread

The Giants are 10-5 in games decided by 5 runs or more. BACK SAN FRANCISCO -1.5 (+155).

Over/Under

Crisscrossing signals here: PASS.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Friday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (24-14) meet the San Francisco Giants (22-15) Friday at Oracle Park to open a 3-game set. First pitch is scheduled for 10:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

San Diego won the rubber match of a 3-game series with the Philadelphia Phillies Thursday 2-0 behind an SP Yu Darvish gem and is 6-4 overall in its last 10 games.

San Francisco is 7-3 overall in its last 10 games but 5 of those wins were against the Colorado Rockies with the other 2 victories coming against the St. Louis Cardinals.

Season series: San Francisco leads 2-1 and has outscored San Diego 17-7 in those meetings.

Padres at Giants projected starters

LHP Sean Manaea vs. RHP Jakob Junis 

Manaea is 2-3 with a 3.77 ERA, 1.12 WHIP, 2.9 BB/9 and 10.5 K/9 in 43 IP over 7 starts.

  • Last start: No-decision in 6-5 loss at the Atlanta Braves with 7 IP, 3 ER, 6 H, 1 HR, 2 BB and 12 K.
  • 2022 vs. the Giants: Loss, 2-1, in San Francisco April 13 with 6 IP, 2 ER, 4 H, 2 BB and 6 K.
  • vs. Giants on the current roster: 2.88 FIP with a .253/.310/.390 expected batting average, wOBA and slugging percentage slash line, 20.4 K% and 89.1 mph exit velocity in 93 plate appearances.

Junis is 1-1 with a 1.74 ERA, 0.97 WHIP, 1.7 BB/9 and 7.8 K/9 in 20 2/3 IP over 2 starts and 2 relief appearances.

  • Last start: Loss, 4-0, at the St. Louis Cardinals Saturday with 5 2/3 IP, 2 ER, 6 H, 1 HR, 1 BB and 3 K.

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at  2 p.m. ET.

  • Money line (ML): Padres +105 (bet $100 to win $105) | Giants -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-205) | Giants -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Padres at Giants picks and predictions

Prediction

Padres 4, Giants 2

Money line

LEAN to the PADRES (+105) because Manaea’s pitching peripherals suggest his record will improve and San Diego is 5-3 overall as a road underdog.

Only 1 of Manaea’s 4 pitches has a plus-run value and most of his swing-and-miss rates have increased year over year, according to Statcast. Manaea’s road ERA (2.70) and WHIP (0.86) are much better than his home marks (5.51 ERA, 1.53 WHIP).

There’s also a line freeze in the betting market since more than 70% of the cash is on the Giants, per Pregame.com, but the line hasn’t budged off the opener.

It’s only a LEAN PADRES (+105) because it hasn’t been profitable fading the Giants at home since the beginning of last season and San Francisco’s lineup has been much hotter at the plate over the past two weeks.

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Run line/Against the spread

PASS because the Padres +1.5 (-205) are too expensive even though San Diego is 7-1 RL as a home underdog and San Francisco is 6-11 RL as a home favorite. Those RL records are appropriately accounted for in the pricing and the Padres +1.5 (-205) isn’t a big enough lock vs. the price.

Over/Under

LEAN to the UNDER 7.5 (-110) only because the Over has cashed in 13 of the last 18 Padres-Giants meetings and the weather forecast is predicting double-digit mph winds blowing out to right-centerfield.

However, San Diego’s lineup is awful vs. right-handed pitching, ranking 22nd in wRC+ (88), 26th in wOBA (.285) and 18th in hard-hit rate (28.8%), according to FanGraphs.

Lastly, there’s a “Pros vs. Joe’s” scenario in the betting market since more money is on the Under but more bets have been placed on the Over. Since professional bettors put up more dough than the average Joe, the money column is considered the sharper side of the market.

For what it’s worth, the UNDER 7.5 (-110) is my favorite wager in the Padres-Giants game.

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If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (4-1) meet the San Francisco Giants (2-2) Tuesday in the second of their 3-game set. First pitch at Oracle Park is scheduled for 9:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

San Diego won the series opener Monday 4-2 after scoring 1 run in the 7th and 9th innings to key the victory.

Padres at Giants: Projected starters

San Diego RHP Yu Darvish vs. San Francisco LHP Alex Cobb 

Darvish had a no-decision versus the Arizona Diamondbacks on Opening Day despite throwing 6 innings of no-hit ball with 3 K and 4 BB. Arizona scored 4 runs in the bottom of the 9th to steal the game, and Darvish’s victory, 4-2.

  • 2021 vs. Giants: 1-1 with a 5.82 ERA (21 2/3 IP, 14 ER), 1.20 WHIP and 12.9 K/9 in 4 starts.
  • vs. Giants on the current roster: 6.80 FIP with a .243 batting average (BA), .365 wOBA, .485 expected slugging percentage (xSLG), 28.0 K% and 89.2 exit velocity (EV) in 82 plate appearances (PA).

Cobb is making his Giants debut and first start of the season Tuesday. He was 8-3 in 2021 with a 3.76 ERA (93 1/3 IP, 39 ER), 1.26 WHIP, 3.2 BB/9 and 9.5 K/9 in 18 starts for the Los Angeles Angels.

  • 2021 vs. Padres: Never faced San Diego.
  • vs. Padres on the current roster: 8.32 FIP with a .260 BA, .368 wOBA, .728 xSLG, 11.1 K% and 95.9 mph EV in 54 PA.

Padres at Giants odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:19 p.m. ET.

  • Money line (ML): Padres -108 (bet $108 to win $100) | Giants -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+155) | Giants +1.5 (-190)
  • Over/Under (O/U): 7.5 (O: -108 | U: -112)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Padres at Giants prediction and picks

Prediction

Giants 4, Padres 3

Money line

BET the GIANTS (-112) because they have better bullpen pitching and are more productive at the plate versus right-handed pitchers since the beginning of last season than the Padres (-108).

Furthermore, nearly three-fourths of the market is on San Diego (according to Pregame.com) primarily because of Darvish’s Opening Day performance and Cobb being at the bottom of San Francisco’s rotation.

However, Cobb had a sneaky impressive 2021 whereas Darvish struggled after the MLB enacted the sticky substance policy. Granted, Darvish was lights out versus the D-backs but Arizona is projected to finish in the cellar of the NL West.

On the other hand, Cobb’s FIP and xFIP were lower than his ERA last season, which suggests progression, and Cobb only allowed 0.48 home runs per 9 innings.

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Run line/Against the spread

PASS. 

Both pitching units have looked solid to start the season and I’m higher on San Diego than San Francisco entering this season so I don’t want to spend for the expensive Giants +1.5 (-190) RL.

Over/Under

LEAN UNDER 7.5 (-112) because Cobb is underrated and I’m willing to give Darvish a mulligan for his disastrous 2021.

Also, per Pregame.com, this is a Pros vs. Joe’s scenario in the betting market with more money coming on the Under but more bets have been placed on the Over.

Oddsmakers have reacted to the cash by lowering the total from the 8-run opener and typically it’s wise to follow the money when it’s opposite of the public since wiseguys put up more dough than your average Joe.

That said, it’s only a LEAN to the UNDER 7.5 (-112) because we are getting to the party a little late on the total and I feel stronger about San Francisco’s ML.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow Geoff Clark on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Monday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (3-1) head up to the Bay Area to play the NL West co-tenant San Francisco Giants (2-1) Monday at Oracle Park. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

San Diego clobbered the Arizona Diamondbacks Thursday-Sunday outscoring them 20-11. Padres LF Jurickson Profar hit the cover off the ball with a .400 batting average (BA), 2 HR and 6 RBI versus the D-Backs.

San Francisco eked out a 2-1 series win over the Miami Marlins by winning the rubber match Sunday 3-2 as all three games were decided by 1 run.

The Giants won the 2021 season series with the Padres 11-8 and San Francisco outscored San Diego 92-76.

Padres at Giants: Projected starters

San Diego RHP Nick Martinez vs. San Francisco LHP Alex Wood

Martinez makes his Padres debut Monday and his first MLB start since 2017. He pitched for the Texas Rangers in the first four seasons of his career from 2014 to 2017. Martinez has spent his last four years pitching for the Nippon Professional Baseball league in Japan.

Wood was 10-4 in 2021 with a 3.83 ERA (138 2/3 IP, 59 ER), 1.18 WHIP, 2.5 BB/9 and 9.9 K/9 over 26 starts.

  • Wood didn’t face San Diego last season despite playing in the same division.
  • vs. Padres on the current roster: 2.46 FIP with a .219 BA, .247 wOBA, .342 expected slugging percentage, 25.0 K% and 90.9 mph exit velocity in 36 plate appearances.

Padres at Giants odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:27 p.m. ET.

  • Money line (ML): Padres +125 (bet $100 to win $125) | Giants -155 (bet $155 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-165) | Giants -1.5 (+133)
  • Over/Under (O/U): 8.5 (O: -105 | U: -120)

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Padres at Giants prediction and picks

Prediction

Padres 4, Giants 3

Money line

LEAN PADRES (+125) because who knows how Martinez will look after spending the last four years in Japan. However, I’m seeing some reverse line movement towards San Diego in the betting market.

A vast majority of the action is on the Giants (-155) but their ML price has decreased from the opener according to both Pregame.com and VegasInsider.com, It’s a red flag whenever sportsbooks make the more popular team cheaper.

However, I’m higher on San Diego than San Francisco coming into 2022 and I think we are getting a good price on the PADRES (+125).

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Run line/Against the spread

PASS because the Padres +1.5 (-165) is too expensive considering the Giants -1.5 (+133) have the second-best RL record versus divisional foes since the beginning of last season at 51-30 RL.

Over/Under

LEAN UNDER 8.5 (-120) because San Diego’s lineup struggled versus left-handed pitching last season and San Francisco’s bullpen was phenomenal last season.

For instance, the Padres are 24th in hard-hit rate and 20th in wRC+ against lefty pitching since the beginning of 2021. Also, the Giants’ relievers are second in xFIP and sixth in WAR over that span.

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San Diego Padres at San Francisco Giants odds, picks and prediction

Analyzing Saturday’s San Diego Padres at San Francisco Giants odds and lines, with expert MLB picks and predictions.

The San Diego Padres (78-82) face the San Francisco Giants (106-54) in the second game of their final three-game series of the season. First pitch is 4:05 p.m. ET Saturday at Oracle Park. Let’s analyze the lines around the Padres vs. Giants odds with MLB picks and predictions.

Padres RHP Joe Musgrove (11-9, 3.22 ERA) makes his 31st start and 32nd appearance. He has a 1.10 WHIP, 2.8 BB/9 and 10.2 K/9 through 176 1/3 IP.

  • The Padres are 1-3 in his four previous starts against the Giants this season.
  • Needs just 1 strikeout to reach 200 in a season for the first time in his career.

Giants RHP Kevin Gausman (14-6, 2.87 ERA) makes his 33rd start. He has a 1.04 WHIP, 2.4 BB/9 and 10.8 K/9 through 185 IP.

  • Has already set career-bests in ERA, strikeouts and WHIP.
  • The Giants are 4-1 in his five starts against the Padres this season.

Padres at Giants odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 10:45 a.m. ET.

  • Money line: Padres +140 (bet $100 to win $140) | Giants -175 (bet $175 to win $100)
  • Against the spread/ATS: Padres +1.5 (-150) | Giants -1.5 (+122)
  • Over/Under: 7.5 (O: -130 | U: +105)

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Prediction

Giants 5, Padres 3

Money line (ML)

The Giants shut out the Padres 3-0 in the series opener on Friday and have won seven games in a row. They have 22 wins in their last 27 games and can clinch the NL West with just one more victory. San Francisco has won three of its last four against San Diego.

The Padres are reeling to end the season. They have lost seven straight and have only three wins in their last 20 games, although all three of those games were against the Giants. San Diego is 7-10 against San Francisco this season.

Take the GIANTS (-175).

Run line/Against the spread (ATS)

The Padres covered the spread in only two of their last 10 games. They are 74-86 ATS overall and 39-40 ATS on the road. Six of their last eight losses have come by at least 2 runs.

16 of the Giants’ last 22 wins have been by at least two runs. They are No.1 in baseball with a 97-63 ATS record and will be focused on getting that one final, clinching win today.

Take the GIANTS -1.5 (+122).

Over/Under (O/U)

11 of the 17 games between the clubs had totals of 8 or more runs.

13 of Gausman’s last 14 starts had totals of 8 or more runs.

Take OVER 7.5 (-130).

For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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San Diego Padres at San Francisco Giants odds, picks and prediction

Analyzing Friday’s San Diego Padres at San Francisco Giants odds and lines, with expert MLB picks and predictions.

The San Diego Padres (78-81) open their final series of the year against the NL West-leading San Francisco Giants (105-54) Friday. First pitch is at 9:45 p.m. ET at Oracle Park. Let’s analyze the lines around the Padres vs. Giants odds with MLB picks and predictions.

Padres RHP Pedro Avila is making his first MLB start of the year and only the second start of his career.  He appeared in 36 games, starting 11, between Double-A San Antonio and Triple-A El Paso. He was 2-4 with a 4.22 ERA, 1.35 WHIP, 4.3 BB/9 and 9.9 K/9 through 74 2/3 IP.

  • His only other major league appearance was in 2019. He had a no-decision in a 7-6 win over the Arizona Diamondbacks and pitched 5 1/3 innings, allowing only 1 run on 4 hits.
  • He is the Padres’ No. 21-ranked prospect.

Giants RHP Anthony DeSclafani (12-7, 3.26 ERA) makes his 31st start. He has a 1.10 WHIP, 2.3 BB/9 and 8.2 K/9 through 162 2/3 IP.

  • This will be his fifth start of the year against the Padres. He is 1-1 with a 3.13 ERA and the Giants are 3-1 in those games.
  • The Giants are 20-10 in his starts and have won four of his last five outings.

Padres at Giants odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 6:15 p.m. ET.

  • Money line: Padres +175 (bet $100 to win $175) | Giants -220 (bet $220 to win $100)
  • Against the spread/ATS: Padres +1.5 (-115) | Giants -1.5 (-105)
  • Over/Under: 8.5 (O: -130 | U: +105)

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Prediction

Giants 7, Padres 5

Money line (ML)

The Padres have lost six games in a row and have only one win in their last 12 games. They are 7-9 against the Giants this season and their three wins over the Giants are their only wins in their last 19 games. They have only 11 wins since Aug. 11.

The Giants have won six games in a row and eight of their last nine, holding a two-game lead over the Los Angeles Dodgers in the NL West with three games to play. With the division still up for grabs and the Padres struggling and with nothing to play for other than pride, they are a bad bet this weekend.

Take the GIANTS (-220).

Run line/Against the spread (ATS)

The Padres are only 7-12 ATS in their last 19 games. Ten of their last 16 losses were by at least 2 runs. They are 39-39 ATS on the road.

Seven of the Giants’ last 11 wins were by at least 2 runs. They have the best ATS record in the majors at 96-63 ATS and are No. 3 at home at 42-36 ATS.

Take the GIANTS -1.5 (-105).

Over/Under (O/U)

Fourteen of the last 20 games for the Padres had a total of 9 or more runs.

Seventeen of the Giants’ last 23 games finished with a total of at least 9 runs.

Half of the 16 games between the two teams had a total of 9 or more, but those eight came in the last 10 games against one another.

Take OVER 8.5 (-130).

For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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San Diego Padres at San Francisco Giants odds, picks and prediction

Analyzing Thursday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (75-70) meet the San Francisco Giants (95-51) Thursday at Oracle Park for the finale of their four-game series. First pitch is scheduled for 3:45 p.m. ET. Let’s analyze the lines around the Padres vs. Giants odds with MLB picks and predictions.

San Francisco steamrolled San Diego in the first two games of this series by a combined score of 15-2 but the Padres snapped the Giants’ nine-game win streak by beating them 9-6 Wednesday.

Also see: 2021 World Series odds for all teams

Season series: Giants lead 7-5.

RHP Pierce Johnson is San Diego’s projected opener for what’s most likely a bullpen day. He is 3-3 with a 2.98 ERA (51 1/3 IP, 17 ER), 1.21 WHIP, 4.2 BB/9 and 11.7 K/9 across one start and 55 relief appearances.

  • Last five outings: 0-0 (team record is 1-4) with 5 IP, 2 ER, 4 H, 1 BB and 4 K in appearances against the Giants, the Los Angeles Dodgers (twice) and Houston Astros (twice).
  • Johnson has made four relief appearances against the Giants this season with 1 ER, 1 H, 2 BB and 5 K over 4 1/3 IP.
  • vs. Padres on the current roster (22 PA): 2.02 FIP with a .200 batting average (BA), .223 wOBA, .302 expected slugging percentage (xSLG), 27.3 K% and 89.8 mph exit velocity (EV).

RHP Kevin Gausman makes his 30th start for the Giants. He is 14-5 with a 2.65 ERA (170 IP, 50 ER), 1.01 WHIP, 2.5 BB/9 and 10.6 K/9 this season.

  • Last outing: Win, 14-5, with 6 IP, 3 ER, 8 H, 0 BB and 9 K Saturday at the Chicago Cubs.
  • Gausman is 2-0 with a 1.42 ERA (19 IP, 3 ER), 14 H, 3 BB and 18 K in three starts against the Padres in 2021.
  • vs. Padres on the current roster (136 PA): 2.11 FIP with a .252 BA, .274 wOBA, .395 xSLG, 27.9 K% and 88.8 mph EV.

Padres at Giants odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 1:15 p.m. ET.

  • Money line: Padres +160 (bet $100 to win $160) | Giants -200 (bet $200 to win $100)
  • Against the spread/ATS: Padres +1.5 (-135) | Giants -1.5 (+110)
  • Over/Under: 8.5 (O: +105 | U: -130)

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Prediction

Giants 6, Padres 2

Money line (ML)

Slight “LEAN” to the GIANTS (-200) even though there’s significant “reverse line movement” (RLM) because they have an edge in the three most important phases of baseball (starting and relief pitching and hitting).

Nearly 90% of the cash wagered at the time of writing and more than three-fourths of the bets are on the Giants, according to Pregame.com, but their money line has been brought down from the -235 consensus opener.

Typically, I’d be leery of betting into RLM but, perhaps San Francisco opened as too big of a favorite and the market has beaten this game into the proper pricing.

Also, I’d entertain throwing San Francisco’s money line into a parlay with another similarly priced favorite for a plus-money payout because this is such a good spot for the Giants.

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Run line/Against the spread (ATS)

“LEAN” to the GIANTS -1.5 (+110) for a half unit because Gausman should at least show up on the NL Cy Young ballot this season and San Diego’s bullpen has been terrible lately.

Over the past two weeks, Padres relievers have the worst WAR, sixth-worst xFIP and fourth-worst HR/9. On top of that, the Giants are 41-22 ATS against NL West foes and 30-23 ATS as home favorites while the Padres are just 29-37 ATS in divisional games.

I’d prefer to lay it with GIANTS -1.5 (+110) than bet San Francisco’s money line outright or parlaying it. My hesitation with betting the Giants -1.5 (+110) heavier is we have the same RLM in the ATS market as well.

Over/Under (O/U)

“LEAN” to the UNDER 8.5 (-130) for a half unit because we have a “pros vs. joes” scenario in the betting market with the presumed “sharp” money on the Under whereas the public is backing the Under.

Typically, it’s profitable in sports betting to follow the money when it’s flowing in the opposite direction as the public. More importantly, San Diego’s lineup has been the most disappointing in the majors since the All-Star break. That’s mostly due to lofty expectations, partially set by the market but also due to the level of talent San Diego sends to the plate.

For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow Geoff Clark on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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