The Dallas Cowboys (4-1) have a road tilt with the New England Patriots (2-3) in Week 6. Kickoff from Gillette Stadium is set for 4:25 p.m. ET Sunday. Below, we look at the Cowboys vs. Patriots odds and lines; check back for our NFL picks and predictions.
The Cowboys picked up their fourth straight win with a 44-20 victory over the NFC East foe New York Giants in Week 5. Just a few days ahead of the one-year anniversary of his season-ending ankle injury QB Dak Prescott connected on 22 of his 32 passes for 302 yards and 3 touchdowns against 1 interception.
RB Ezekiel Elliott eclipsed 100 rushing yards for the second consecutive week as he finished with 110 yards and a touchdown on 21 carries. WR CeeDee Lamb bounced back from a quiet Week 4 and recorded 84 yards and a score on 4 receptions from 6 targets.
The Patriots snapped a two-game losing skid with a 25-22 road victory over the Houston Texans. New England was without four of its starting offensive linemen but managed to protect rookie QB Mac Jones, although the run game looked suspect at times. The Pats overcame a 22-9 deficit that they found themselves in just 90 seconds into the second half.
Jones finished with 23-for-30 passing for 231 yards with 1 touchdown and 1 interception. TE Hunter Henry led all Patriots’ pass catchers with 75 receiving yards (and caught Jones’ lone touchdown), while RB Damien Harris paced the running back group with 58 yards and a score on 14 carries.
Cowboys at Patriots odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 11:33 a.m. ET.
- Money line: Cowboys -205 (bet $205 to win $100) | Patriots +165 (bet $100 to win $165)
- Against the spread (ATS): Cowboys -4.5, -105 (bet $105 to win $100) | Patriots +4.5, -115 (bet $115 to win $100)
- Over/Under (O/U): 49.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)
Also see: Betting 101
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2021 betting stats:
- ML: Cowboys 4-1 | Patriots 2-3
- ATS: Cowboys 5-0 | Patriots 2-3
- O/U: Cowboys 4-1 | Patriots 1-4
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Cowboys at Patriots head-to-head
The Cowboys and Patriots have only met 13 times since 1971, most recently a 13-9 New England victory in 2019. Dallas leads the all-time series 7-6, but New England have won six in a row after losing the first seven times the two sides met.
Despite that win streak, this weekend will feature a very different look as the last five meetings featured future Hall of Fame QB Tom Brady who is no longer with the Patriots.
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