College Football Playoff 2022: Game lines for top-6 teams in second rankings

Which top six teams are on upset alert after the second College Football Playoff ranking?

The first iteration of the College Football Playoff rankings this season have already crumbled.

Last week’s No. 3 team, Michigan State, went from knocking off rival Michigan at home to an 11-point loss at Purdue while every other top six team found a way to win. That should get a bit easier for some of the top teams in the CFP committee’s second rankings as a number of schools prepare for matchups that’d be more enticing in early September than mid November.

Once again, it’ll be a team outside the top six with the biggest opportunity to impact the rankings as No. 19 Purdue travels to Columbus for a showdown with Ohio State.

Let’s dig into this week’s lines as the stakes continue to get higher.

All odds via Tipico Sportsbook.