Buffalo Bills at Baltimore Ravens odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at Baltimore Ravens odds and lines, with expert NFL picks, predictions and best bets.

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The Buffalo Bills (2-1) come into M&T Bank Stadium Sunday to face the Baltimore Ravens (2-1) in 1 of Week 4’s marquee matchups. Kickoff is at 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Bills vs. Ravens odds, and make our expert NFL picks and predictions.

Both the Bills and the Ravens each have 1 loss — to the Miami Dolphins.

In Week 2 against the Dolphins, the Ravens controlled the game until the 4th quarter when QB Tua Tagovailoa went off, leading Miami to a 42-38 victory. Dolphins WRs Tyreek Hill and Jaylen Waddle became the 1st teammates since Don Hutson and Andy Uram of the 1942 Green Bay Packers to finish with 170-plus receiving yards and 2 TDs each in the same game.

For the Bills, they also completely controlled the game against the Dolphins, but they just could not find the end zone enough in a 21-19 loss last Sunday. QB Josh Allen threw for 400 yards and 2 TDs on 63 attempts, while the Bills outgained the Dolphins 497 yards to 212 yards. Despite this, Miami figured out a way to win.

The Bills and Ravens are both really good teams. This should be a great game between 2 MVP front-runners in Allen and Baltimore QB Lamar Jackson, who both have the ability to extend plays with their legs.

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Bills at Ravens odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 6:40 p.m. ET.

  • Money line (ML): Bills -160 (bet $160 to win $100) | Ravens +135 (bet $100 to win $135)
  • Against the spread (ATS): Bills -3.5 (+100) | Ravens +3.5 (-125)
  • Over/Under (O/U): 50.5 (O: -120 | U: -105)

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Bills at Ravens key injuries

Bills

  • WR Stefon Diggs (lower body) questionable
  • SS Micah Hyde (neck) out
  • CB Dane Jackson (neck) questionable
  • DL Ed Oliver (ankle) questionable
  • CB Tre’Davious White (ACL/knee) out

Ravens

  • RB Gus Edwards (ACL/knee) out
  • CB Kyle Fuller (ACL/knee) out
  • LB Justin Houston (groin) questionable
  • DL Michael Pierce (arm) questionable
  • OL Ronnie Stanley (ankle) questionable

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Bills at Ravens picks and predictions

Prediction

Bills 37 Ravens 24

Money line

NO BET.

I love the Bills in this game. When they win, they win big. So, there is no need to take the ML. If you like the Ravens, I suggest the ML +135 rather than the +3.5 (-125).

Against the spread

TAKE BILLS -3.5 (+100).

When the Bills win, they win big. In their last 7 victories, dating to last season, the Bills have not won by less than 10 points. In Week 2 this year and in the wild-card playoff game last season, they won by more than 30. Like I said, I love the Bills this week. So, expect this game not to be close.

Over/Under

WAIT TO MAKE A PLAY.

With Hurricane Ian moving up the East Coast, the weather for this game could be an issue. If the storms move past, or do not develop, I LEAN OVER 50.5 (-120).

If the storms do hit during the game, the Ravens will slow the game down immensely by running the ball. This will cause far less possessions for both teams and the Under is likely to hit.

Make sure to check the forecast before putting any wager on this one.

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Buffalo Bills at Miami Dolphins odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at Miami Dolphins odds and lines, with expert NFL picks, predictions and best bets.

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The Buffalo Bills (2-0) head to Hard Rock Stadium Sunday to take on the Miami Dolphins (2-0) in an early season divisional matchup to determine who will stay unbeaten. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Bills vs. Dolphins odds, and make our expert NFL picks and predictions.

The Bills are coming off a massive 41-7 Monday night victory over the Tennessee Titans. QB Josh Allen had another MVP-caliber game throwing for 317 yards and 4 TDs, hitting on 26 of 38 attempts. His top target was WR Stefon Diggs, who had 12 receptions for 148 yards and 3 TDs. Allen spread the ball around the offense with 8 players having at least 1 reception. The Bills defense played phenomenal as well, forcing 4 turnovers and holding the Titans to only 187 total yards.

The Bills have looked unstoppable in 2 games which is why Buffalo is the early season Super Bowl favorite.

Miami won an offensive shootout last week against the Baltimore Ravens 42-38. Down 35-14 entering the 4th quarter, the Dolphins outscored the Ravens 28-3 to claim the Week 2 victory. QB Tua Tagovailoa had a slow start, throwing 2 INTs, but he ended the game with 469 yards and 6 TDs. His top 2 receivers, WR Tyreek Hill and WR Jaylen Waddle, each showed their abilities with Hill having 11 receptions for 190 yards and 2 TDs while Waddle had 11 catches for 171 yards and 2 TDs. TE Mike Gesicki (4, 41, 1) also had a nice day to open up the offense.

The Dolphins defense will be a focal point this week against the Bills. Although they locked in late, only giving up 3 points in the final quarter, they struggled to contain duel-threat QB Lamar Jackson. Playing another duel-threat QB in Allen, they will just to adjust on the fly and contain him. Tua and company will have to have another big game in what is expected to be yet another offensive shootout.

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Bills at Dolphins odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:47 a.m. ET.

  • Money line (ML): Bills -210 (bet $210 to win $100) | Dolphins +175 (bet $100 to win $175)
  • Against the spread (ATS): Bills -4.5 (-110) | Dolphins +4.5 (-110)
  • Over/Under (O/U): 53.5 (O: -105 | U: -115)

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Bills at Dolphins key injuries

Bills

  • Micah Hyde (neck) out
  • CB Dane Jackson (neck) out
  • DT Ed Oliver (ankle) out
  • DT Jordan Phillips (ankle) out
  • MLB Matt Milano (neck) unspecified
  • FS Jordan Poyer (foot) questionable
  • WR Gabe Davis (ankle) questionable

Dolphins

  • CB Xavien Howard (groin) questionable
  • DT Raekwon Davis (knee) questionable

[the_huddle]

Bills at Dolphins picks and predictions

Prediction

Bills 38, Dolphins 35

Money line

Lean BILLS (-210). Allen and the offense will make up for their defensive injuries. So far this season, the Bills have been able to consistently convert when they get to the red zone and that will need to continue in order to beat the Dolphins.

Against the spread

DOLPHINS +4.5 (-110) is the play. The Dolphins are on an ATS hot streak at home and in September. They are 6-1 ATS in their last 7 games in September and 6-1 ATS in their last 7 home games. With so many critical injuries to the Buffalo defense, Miami has the offensive fire power to stay close in this game. Hill and Waddle will open up the offense with their top-level speed while Tagovailoa and RBs Raheem Mostert and Chase Edmonds will keep the defense on their toes on the ground.

Over/Under

Take the OVER 53.5 (-105). Both these teams have many offensive weapons and coaches who know who to get them open. For the Bills, Allen is great at moving the ball around the offense and getting it to any player who is open. For the Dolphins, Tagovailoa is working with the speed of Hill and Waddle who can win their matchups more times than not.

The Over is 4-0 in the Bills last 4 games following a straight up win of more than 14 points, coach Josh McDaniel and Allen have a chemistry together that understand how to put the ball in the end zone. Furthermore, the Over is 10-4 in the last 14 meetings between these 2 teams.

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Tennessee Titans at Buffalo Bills odds, picks and predictions

Analyzing Monday’s Tennessee Titans at Buffalo Bills Week 2 odds and lines, with expert NFL picks, predictions and best bets.

The Tennessee Titans (0-1) and Buffalo Bills (1-0) play a Week 2 matchup Monday at Highmark Stadium. Kickoff is set for 7:15 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook‘s lines around the Titans vs. Bills odds, and make our expert NFL picks and predictions.

The Titans blew a 13-point lead in a 21-20 loss vs. the New York Giants in their season opener Sept. 11. Tennessee K Randy Bullock missed a potential game-winning 47-yard field goal wide left as time expired. Titans QB Ryan Tannehill threw for 266 yards and 2 TDs. Tennessee was outgained by New York 394-359 in total offense, despite holding the Giants to just 133 yards in the 1st half.

Bills QB Josh Allen threw for 297 yards, 3 TDs and 2 INTs in a 31-10 win at the defending Super Bowl champion Los Angeles Rams Sept. 8. Allen was impressive in the 2nd half, completing a 47-yard pass to WR Gabe Davis and a 53-yard TD pass to WR Stefon Diggs. He finished 26-of-33 passing (83.9%) and broke Buffalo’s completion percentage record for a regular season game.

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Titans at Bills odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 6:16 p.m. ET.

  • Money line (ML): Titans +380 (bet $100 to win $380) | Bills -500 (bet $500 to win $100)
  • Against the spread (ATS): Titans +9.5 (+100) | Bills -9.5 (-120)
  • Over/Under (O/U): 47.5 (O: -103 | U: -117)

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Titans at Bills key injuries

Titans

  • CB Kristian Fulton (hamstring) out
  • RB Dontrell Hilliard (hamstring) out
  • WR Kyle Phillips (shoulder) questionable

Bills

  • WR Gabe Davis (ankle) questionable
  • CB Dane Jackson (knee) probably
  • DL Ed Oliver (ankle) out
  • DL Tim Settle (calf) doubtful

[the_huddle]

Titans at Bills picks and predictions

Prediction

Bills 24, Titans 16

Money line

The Bills (-500) money line is too expensive to bet, especially in a potential let-down game after a primetime win over the defending Super Bowl champions in Week 1.

PASS.

Against the spread

This line originally opened at -7 at most books. While I did like the Bills at -7, Buffalo has received way too much action and the line is now inflated. This is too many points for a Tennessee team that was the No. 1 seed in the AFC in the 2021-22 playoffs.

BET THE TITANS +9.5 (+100).

Over/Under

The Under is 4-1 in Tennessee’s last 5 games after failing to cover the spread. Tennessee’s defense should be extra focused Monday vs. the Super Bowl favorites after losing to the Giants in Week 1.

BET UNDER 47.5 (-117).

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Buffalo Bills at Los Angeles Rams odds, picks and predictions

Analyzing Thursday’s Buffalo Bills at Los Angeles Rams Week 1 odds and lines, with expert NFL picks, predictions and best bets.

What better way to kick off the 2022 NFL season than with the defending champions hosting the Super Bowl favorites? That’s what we have Thursday night with the Los Angeles Rams taking on the Buffalo Bills at SoFi Stadium. Kickoff is set for 8:20 p.m. ET (NBC) from Inglewood. Below, we analyze Tipico Sportsbook‘s lines around the Bills vs. Rams odds, and make our expert NFL picks and predictions.

The Rams are the reigning Super Bowl champions after beating the Cincinnati Bengals in February in their home stadium. They’re among the betting favorites in the NFC, close behind the Tampa Bay Buccaneers and Green Bay Packers. Though they suffered some key losses in the offseason, including OLB Von Miller and RG Austin Corbett, the Rams are built to contend for another championship this season.

The Bills are the betting favorites to win it all this season after coming close to reaching the big game last year. Led by QB Josh Allen, the Bills added Miller in free agency and return star players such as CB Tre’Davious White and WR Stefon Diggs. They boasted the No. 1 defense in football last season, but that very defense was unable to stop the Chiefs in the AFC divisional round last postseason.

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Bills at Rams odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 7:11  p.m. ET.

  • Money line (ML): Bills -135 (bet $135 to win $100) | Rams +115 (bet $100 to win $115)
  • Against the spread (ATS): Bills -2.5 (-115) | Rams +2.5 (-105)
  • Over/Under (O/U): 51.5 (O: -112 | U: -108)

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Bills at Rams key injuries

Bills

  • OL Tommy Doyle (foot) questionable
  • TE Quintin Morris (hamstring) questionable

Rams

  • WR Van Jefferson (knee) questionable

[the_huddle]

Bills at Rams picks and predictions

Prediction

Rams 30, Bills 24

Money line

It’s rare for the defending Super Bowl champions to be underdogs in the season opener, but that’s more a testament to the Bills’ talent than it is an indictment of the Rams. Los Angeles is just as talented as it was last season, even with the losses it suffered in free agency.

The Rams are 5-0 in Week 1 under Sean McVay and I don’t think this will be the first time he loses a season opener. I like the RAMS (+115) to win outright, especially being at home and with the line sitting at plus-money.

Against the spread

As good as the Rams have been in season openers under McVay, they’re also perfect against the spread. They’re 5-0 ATS in Week 1 the last 5 years, and now they’re getting 2.5 points at home against the Bills.

The better value is still in taking the Rams to win outright at +115, but even taking them +2.5 at -105 is worth a bet. Take the RAMS +2.5 (-105) to cover the spread, though I’d make it a smaller wager as insurance for your ML bet.

Over/Under

The Rams and Bills are both expected to be among the most explosive offenses in the NFL, and that will be on display Thursday night. In limited preseason action, the Bills offense looked sharp and as good as expected.

This will be the 1st game action for the Rams starters, but I don’t think it’ll take them long to get going. They dropped 34 in Stafford’s debut last season against the Chicago Bears. Give me the OVER 51.5 (-112).

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Denver Broncos at Buffalo Bills odds, picks and prediction

Analyzing Saturday’s Denver Broncos at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (1-0) welcome the Denver Broncos (1-0) to Highmark Stadium Saturday. Kickoff is set for 1 p.m. ET (NFL Network). Below, we analyze Tipico Sportsbook‘s lines around the Broncos vs. Bills odds, and make our best NFL picks, predictions and bets.

Both teams enter this battle with ultra-high expectations this season. The Broncos added star QB Russell Wilson this offseason. Wilson didn’t play in the team’s Week 1 preseason home win over the Cowboys.

The Broncos won 17-7 with QB Josh Johnson doing most of the heavy lifting, going 16-for-23 for 172 yards and 2 touchdowns. I would expect at least some showing from starting receivers and rushers against Buffalo.

The Bills, on the other hand, won 27-24 at against the visiting Colts in one of the more thrilling Week 1 games. Superstar QB Josh Allen was never going to see the field, and the Bills actually won despite a combined 3 interceptions by their quarterbacks.

QB Matt Barkley was 18-for-24 for 224 yards and 1 interception, while projected backup QB Case Keenum was 11-for-18 for 86 yards and 2 picks. I’d expect see some Allen in this matchup.

Broncos at Bills odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:50 a.m. ET.

  • Money line (ML): Broncos +250 (bet $100 to win $250) | Bills -320 (bet $320 to win $100)
  • Against the spread (ATS): Broncos +6.5 (-103) | Bills -6.5 (-117)
  • Over/Under (O/U): 42.5 (O: -108 | U: -112)

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Broncos at Bills picks and predictions

Prediction

Bills 21, Broncos 17

Money line

PASS.

There’s not much value here either way, especially for Buffalo. I wouldn’t bet a -320 preseason favorite.

Against the spread

BET BRONCOS +6.5 (-103).

The Broncos looked strong on both ends of the field against the Cowboys, and Johnson was fantastic.

Given he should be going against a Bills secondary that doesn’t play its terrific safety duo much, Johnson should be able to see similar success. At almost a touchdown, the value here is on Denver to cover.

The Bills looked awful despite winning their opener. Their quarterbacks threw 3 interceptions, and with Allen not set to play too much, I expect another tough outing for Buffalo.

Backup RB Zack Moss did play, but I would expect the starters to get limit reps Saturday. The Broncos looked stronger in their opener, and I’d back them here.

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Over/Under

LEAN UNDER 42.5 (-112).

The quarterback play in the Bills-Colts game was horrific, which often helps points being scored.

I don’t expect that to continue, and while Buffalo should have one of the top high-powered offenses in the league, it could certainly struggle without Allen.

Buffalo had a fumble return and two 4th-quarter touchdowns against Indy. For 3 quarters, its offense did nothing, and that’s concerning.

With the Broncos also unlikely to play many starters and Johnson having not found a true NFL home given he’s a mid-level backup, they may struggle as well.

Overall, the UNDER 42.5 (-112) feels like the better play.

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Buffalo Bills at Kansas City Chiefs odds, picks and prediction

Analyzing Sunday’s Buffalo Bills at Kansas City Chiefs AFC Divisional Round odds and lines, with expert NFL picks, predictions and best bets.

The third-seeded Buffalo Bills (12-6) face the second-seeded Kansas City Chiefs (13-5) Sunday in a rematch of last season’s conference championship in the AFC Divisional Round. Kickoff at Arrowhead Stadium is scheduled for 6:30 p.m. ET (on CBS). Below, we look at the Bills vs. Chiefs odds and lines, and make our best NFL picks, predictions and bets.

The third-seeded Bills won their fifth straight game by crushing the New England Patriots 47-17 in an AFC Wild Card game as 4.5-point road underdogs. The Bills are 10-6-2 against the spread (ATS) and 9-9 Over/Under (O/U).

The Chiefs, the No. 2 seed, handled business as 11-point home favorites in their Wild Card matchup by dismantling the Pittsburgh Steelers 42-21 for their 10th win in the past 11 games. The Chiefs are 9-9 ATS and 11-7 O/U.

The Bills whooped the Chiefs 38-20 in Week 5 as 2.5-point road underdogs. Buffalo had 3.1 more yards per play than K.C., was better in the red zone and on third down and had a plus-4 in turnover margin.

Also see: All Divisional Round odds and lines

Bills at Chiefs odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11:04 p.m. ET.

  • Money line: Bills +102 (bet $100 to win $102) | Chiefs -125 (bet $125 to win $100)
  • Against the spread: Bills +1.5 (-108) | Chiefs -1.5 (-112)
  • Over/Under: 53.5 (O: -115 | U: -105)

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Bills at Chiefs key injuries

Bills

  • None

Chiefs

  • None

Also seeBet Slippin’ Podcast: NFL Divisional Round Weekend

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Bills at Chiefs odds, lines, predictions and picks

Prediction

Bills 34, Chiefs 24

Money line

I’m sticking with my preseason guns and ROLLING with the BILLS (+102) for 1.25 units.

I predicted Buffalo would meet the Los Angeles Rams in Super Bowl LVI on Bet Slippin’s final NFL season preview podcast and see no reason to change my pick.

Bills QB Josh Allen is a bona fide alpha, head coach Sean McDermott is an elite tactician and has paid his playoff dues, and offensive coordinator Brian Daboll is perhaps the hottest head coaching candidate.

Buffalo is fantastic in high-leverage situations. The Bills have the best third-down conversion differential in the NFL and the sixth-best, red-zone scoring differential.

Buffalo is structured perfectly to go against Kansas City. The Bills have possibly the best safety tandem in the league (FS Micah Hyde and SS Jordan Poyer) and one of the best coverage linebackers in Matt Milano.

Chiefs TE Travis Kelce playing well is crucial for K.C.’s offense and the Bills have the coaching and players to neutralize Kelce.

Buffalo’s defense can force Chiefs QB Patrick Mahomes into being precise up-and-down the field. We’ve seen Mahomes get antsy and throw the ball into tight windows if opponents eliminate the big play.

Mahomes threw 2 interceptions and just 272 yards on 54 pass attempts in the Week 5 loss to the Bills. Mahomes’ 4.11 adjusted yards gained per pass attempt in that game was his lowest in 63 career starts.

More importantly, the Bills have higher expected points added per play, yards per play differential and pressure rate differentials than the Chiefs.

The only fat on Buffalo’s resume is it had the easiest schedule in the NFL (according to Football Outsiders) and a weird 9-6 loss to the Jacksonville Jaguars in Week 9.

The Bills stomped the Chiefs earlier this season and are playing their best football entering this game. Buffalo’s beatdown of New England in the Wild Card Round is one of the greatest games any team has ever played.

BET the BILLS (+102). But if there’s late line movement toward Kansas City and Buffalo’s spread goes north of +2.5, then I’d sprinkle on the Bills outright and hammer them plus the points.

Against the spread

PASS with a heavy “lean” toward the Bills +1.5 (-108) and I’d take Buffalo’s spread if gets to +2.5 or higher. Either way, the Bills are the right side and I like them to advance to the AFC title game.

Over/Under

PASS because my heart says both offenses play an awesome game Sunday, but my brain says this 53.5 total is too high.

Plus, a majority of the market is betting the Over, which has steamed the total up from the 52.5-point opener, but I hate following the herd in sports betting.

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New England Patriots at Buffalo Bills odds, picks and prediction

Analyzing Saturday’s Super Wild Card Weekend New England Patriots at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

For the third time this season, the AFC East-champion Buffalo Bills (11-6) and New England Patriots (10-7) face off in a big AFC East matchup. This time, it happens during the Super Wild Card Weekend. The game is slated for 8:15 p.m. EST, Saturday at Highmark Stadium. We analyze the Patriots vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

They split games this season; both played during December, so the squads are very familiar with each other. New England won 14-10 at Buffalo Dec. 6, while Buffalo took care of business with a 33-21 road victory Dec. 26, as the two went back-and-forth atop the AFC East.

The Patriots have won four of the last five in Buffalo — the one loss coming last season. Granted, New England has looked very different at quarterback the past two seasons.

In its early December win, Patriots QB Mac Jones attempted just three passes, completing two for 19 yards in poor, windy weather conditions. Instead, they relied on RBs Damien Harris and Rhamondre Stevenson, who combined for 34 carries. Patriots head coach Bill Belichick is the ultimate game master; him relying heavily on the ground game and not on his rookie quarterback tonight would not be surprising.

Weather — at least very cold temps — will play a factor again. While wind is only predicted at 5 m.p.h., it’s expected to be just 4 degrees.

The Bills offense runs through QB Josh Allen, who has been in MVP consideration again this season. He has, however, struggled at home vs. New England:

  • 2021: 15/30, 145 pass yards, 1 TD, 0 INT, 1 FumL, 2 sacks
  • 2020: 11/18, 154 pass yards, 0 TD, 1 INT, 1 sack
  • 2019: 13/28, 153 pass yards, 0 TD, 3 INT, 4 sacks

Also see: All Wild Card odds and lines

Patriots at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:50 a.m. ET.

  • Money line: Patriots +190 (bet $100 to win $190) | Bills -240 (bet $240 to win $100)
  • Against the spread (ATS): Patriots +5.5 (-112) | Bills -5.5 (-108)
  • Over/Under (O/U): 43.5 (O: -117 | U: -103)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Patriots at Bills key injuries

Patriots

  • RB Damien Harris (hamstring) questionable
  • WR Jakobi Meyers (thigh) questionable
  • OT Isaiah Wynn (hip/ankle) OUT
  • DE Lawrence Guy (shoulder) questionable
  • LB Dont’a Hightower (knee) questionable
  • S Adrian Phillips (knee) questionable
  • PK Nick Folk (shoulder) questionable

Bills

  •  No injuries

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Patriots at Bills odds, lines, predictions and picks

Prediction

Bills 19, Patriots 17

Money line

The Bills are the more talented team, and at -240, the juice on an outright win isn’t too pricey, but my confidence in them winning outright is waning on game day. Belichick will have the Patriots ready with a successful blueprint.

But which Buffalo team will show up?

It’s not that long ago (Nov. 21) Buffalo lost 41-15 at home to the Colts, or 9-6 to the Jaguars on the road. They beat the teams they should have (Panthers, Falcons and Jets) in December but went 1-2 versus playoff teams (New England twice, Tampa Bay), including that loss to this New England team.

I have no problem sprinkling a half-unit on the Patriots at +190 pulling an upset, but it isn’t the best bet to focus on, and I’d prefer to have wiggle room getting some points. PASS.

Against the spread

That said, I’m definitely digging the +5.5 line (-112) for the underdog Patriots, which feels about two points or more too wide in what should be a slow-paced, low-scoring, tight game in freezing temps. 

The Patriots are 10-7 ATS and 6-2 ATS on the road this season. Buffalo is 9-6-2 ATS, but 6-3 at home.

In the last three matchups in Buffalo, just 4.3 points separated the teams on average, with six points being the largest margin in a 2019 New England victory.

Hit the PATRIOTS +5.5 (-112) to cover for a full unit.

Over/Under

Only one of the past five meetings between these teams in Buffalo has gone over 40 points. On the season, Buffalo is 8-9 vs. the O/U, while New England is 9-8.

Both teams rushed for better than 2,150 yards — ranking in the top eight in the league — during the regular season, and both squads use multiple players to get the job done. That kills clock quickly. Look for long, sustained drives and ball-possession football to be the game script from both teams keeping the scoring opportunities lower and driving the score down.

Love the UNDER (43.5, -103) play here for at least a unit, maybe two.

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New York Jets at Buffalo Bills odds, picks and prediction

Analyzing Sunday’s New York Jets at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The New York Jets‘ (4-12) miserable 2021 season will come to a close on Sunday when they visit the playoff-bound Buffalo Bills (10-6). Kickoff for this AFC East tilt from Highmark Stadium will be at 4:25 p.m. ET. Below, we look at the Jets vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

The Jets are coming off a heartbreaking 28-24 loss to the Tampa Bay Buccaneers in Week 17. QB Tom Brady threw a touchdown pass in the final seconds to give the Bucs the win, preventing the Jets from winning their second straight game. The Jets are just 3-7 in their last 10 games, although they have scored at least 24 points in each of their last three.

The Bills are riding a three-game win streak into this one, taking all three of those games by at least 12 points. They’re now in control of the AFC East after beating the New England Patriots two weeks ago, putting themselves in a position to host a playoff game in the wild-card round with a victory Sunday.

Jets at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:53 a.m. ET.

  • Money line: Jets +850 (bet $100 to win $850) | Bills -1800 (bet $1,800 to win $100)
  • Against the spread (ATS): +16.5 (-112) | Bills -16.5 (-108)
  • Over/Under (O/U): 40.5 (O: -112 | U: -108)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Jets at Bills key injuries

Jets

  • WR Braxton Berrios (thigh) out

Bills

  • DE Efe Obada (ankle) out
  • WR Emmanuel Sanders (knee) doubtful

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Jets at Bills odds, lines, predictions and picks

Prediction

Bills 31, Jets 17

Money line

The Bills won 45-17 the last time these teams met. It was a completely dominant performance from a Buffalo team that was favored by 13.5 points in that one. However, the Bills have been susceptible to letdowns as big favorites with outright losses to the Jacksonville Jaguars as 14.5-point favorites and the Indianapolis Colts as 7-point favorites.

I expect the Bills to win this one but it’s not worth a wager at -1800. PASS.

Against the spread

The Jets have played surprisingly well in the last three weeks, keeping things close with the Miami Dolphins and Tampa Bay, and beating Jacksonville by 5 points. They’re 3-0 ATS in their last three games and have built some momentum.

I like the JETS +16.5 (-112) getting the points and covering Sunday.

Over/Under

The Jets have played much better offensively in their last 10 games, and the total has gone over seven times in that span as a result. The Bills have remained steady and scored at least 27 points in five of their last six games, with the only exception being a windy 14-10 loss to the Patriots.

Bet the OVER 40.5 (-112) in this game. The Bills could hit that number themselves.

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Atlanta Falcons at Buffalo Bills odds, picks and prediction

Analyzing Sunday’s Atlanta Falcons at Buffalo Bills odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (9-6) are on a quest to keep their AFC East championship dreams alive Sunday when they host a mediocre Atlanta Falcons (7-8) squad during Week 17 action. Kickoff is scheduled for 1 p.m. ET at Highmark Stadium. Below, we look at the Falcons vs. Bills odds and lines, and make our best NFL picks, predictions and bets.

With snow expected we should be treated to a winter-wonderland game. Daytime accumulation of 1-3 inches is possible, with winds in 9-11 mph territory, which could lead to more emphasis on both ground games.

If you want to compete with Buffalo, you’re going to need to score — something the Falcons struggle doing. Atlanta is poorly ranked this season in most key offensive metrics, averaging just 18.5 points (25th in the league), 309.5 total yards (25th) and 86.2 rush yards (31st) per game.

While Atlanta has won three of their last five games, those wins came against the Detroit Lions, Carolina Panthers and Jacksonville Jaguars. They’re 2-3 against the spread (ATS) and 1-4 O/U during that stretch.

The Bills are also 3-2 in their last five games, but losses came against the Tampa Bay Buccaneers (in OT) and New England Patriots. Buffalo is 3-2 ATS and 3-2 O/U across that span.

Buffalo looks to keep pushing into the playoffs after scoring at least 31 points in each of its last two games, both of which were ATS covers and Over hits. Buffalo averages 28.5 points (3rd in the league), 381.2 total yards (6th) and 120.4 rush yards (11th) per game.

Falcons at Bills odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 10:32 a.m. ET.

  • Money line: Falcons +700 (bet $100 to win $700) | Bills -1200 (bet $1,200 to win $100)
  • Against the spread (ATS): Falcons +14.5 (-112) | Bills -14.5 (-108)
  • Over/Under (O/U): 45.5 (O: -115 | U: -105)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Falcons at Bills key injuries

Falcons

  • CB Fabian Moreau (ribs) doubtful
  • Jaylinn Hawkins (reserve/COVID) questionable

Bills

  • WR Emmanuel Sanders (knee) questionable
  • DT Ed Oliver (ankle) questionable

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Falcons at Bills odds, lines, predictions and picks

Prediction

Bills 26, Falcons 13

Money line

It is an easy PASS on the money line, simply because it’s not smart betting -1200 chalk plays. Even with a more than likely Buffalo win, the return just isn’t worth the risk. Every $100 wagered on Buffalo, who have implied winning odds of 92.31 percent, returns just $8.33.

Atlanta has also not shown enough this season to even dangle a half-unit on a +700 underdog while chasing an upset.

Against the spread

Atlanta is 6-9 ATS while Buffalo is 8-6-1 ATS on the year.

I hate spreads of more than two touchdowns — this one sits at 14.5 currently — as beating a team by 15 is never an easy feat. However, Buffalo has covered a spread this big four times this season, most recently in a 31-14 victory over Carolina Dec. 19th.

Buffalo has every reason to put forth an A+ effort here, while Atlanta is just playing out the schedule. Even then, Atlanta QB Matt Ryan is playing safe, conservative football with just one turnover in the past month and the tandem of RB Cordarrelle Patterson and RB Mike Davis provide an interesting 1-2 punch. The Bills have allowed at least 14 points in each of their past four games.

The LEAN is the FALCONS +14.5 (-112), but I’d only hit it with a half unit.

Over/Under

It’s going to take some effort to get to the total of 45.5 points and I’m not sold Atlanta can do its part in helping with the weather a classic Buffalo-style this time of year.

Buffalo is 8-7 and Atlanta is 6-9 against the O/U. With ground games, clock management and long drives a likely approach today, siding with the UNDER 45.5 (-105) is the safe play here.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and, soon, IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

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Buffalo Bills at New England Patriots odds, picks and prediction

Analyzing Sunday’s Buffalo Bills at New England Patriots Week 16 odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (8-6) and New England Patriots (9-5) meet in a crucial AFC East showdown Sunday at 1 p.m. ET (on CBS). Below, we look at the Bills vs. Patriots odds and lines, and make our best NFL picks, predictions and bets.

The Patriots lead the Bills by one game atop the division. New England took the first head-to-head meeting of the season 14-10 as a 3-point road underdog in Week 13.

In gusty winds, New England QB Mac Jones only attempted 3 passes, completing 2 for 19 yards, and the defense held the Bills to a season-low 230 offensive yards.

RB Damien Harris finished with 111 rushing yards, including a 64-yard touchdown, as the Pats outrushed the host Bills 222 to 99.

The Bills had a chance to take the lead late when they faced 1st-and-10 at the Patriots’ 14-yard line with 2:30 to go, but a 1-yard run followed by three incomplete passes sealed the New England victory.

Also see: All Week 16 odds and lines

Bills at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:54 a.m. ET.

  • Money line: Bills -105 (bet $105 to win $100) | Patriots -115 (bet $115 to win $100)
  • Against the spread (ATS): Bills +0.5 (-105) | Patriots -0.5 (-115)
  • Over/Under (O/U): 43.5 (O: -110 | U: -110)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

Bills at Patriots key injuries

Bills

  • None

Patriots

  • WR Nelson Agholor (concussion) out
  • WR Rhamondre Stevenson (illness) out
  • C David Andrews (shoulder) questionable
  • DT Christian Barmore (knee) questionable
  • LB Ja’Whaun Bentley (ribs, ankle) questionable
  • RB Brandon Bolden (knee) questionable
  • K Nick Folk (knee) questionable
  • RB Damien Harris (hamstring) questionable
  • WR N’Keal Harry (hip) questionable
  • DB Adrian Phillips (knee) questionable

Let’s Make This Interesting

Place your legal sports bets online in New Jersey and Colorado with Tipico Sportsbook, a trusted, global sports-betting leader. Iowa, get ready, Tipico is coming to your state soon! New customer offer: Deposit $10 or more, get $100 in instant bet credits! 21+, see Tipico.com for Terms and Conditions. Bet now!

Bills at Patriots odds, lines, predictions and picks

Prediction

Patriots 30, Bills 24

Money line

PASS and just focus on the spread as they’re the exact same price.

New England is 3-4 straight-up (SU) at home and 3-2 as a home favorite, while Buffalo is 4-3 SU on the road and 1-1 as a road underdog.

Plus, Buffalo QB Josh Allen is 2-4 in his career vs. the Pats.

Against the spread

NEW ENGLAND -0.5 (-115) is the STRONGEST PLAY – 1½ times your usual wager.

The Patriots had not only won seven in a row, they covered seven in a row until a 27-17 loss at the Indianapolis Colts last week in a Saturday matchup.

They are 4-3 ATS at home this season, including 3-0 ATS in their last three at Gillette Stadium. New England is also 5-0 in its last five as a favorite.

The Bills, who snapped a two-game skid with a 31-14 home victory vs. the Carolina Panthers in Week 15, are 2-3 SU/ATS in their last five games.

They have been inconsistent against the spread. They are 4-3 ATS on the road and 0-4 ATS in their last four games following a SU win.

Over/Under

OVER 43.5 (-110) is the way to go.

Don’t expect a game like the last Bills-Pats meeting when New England only threw the ball 3 times. That was in extremely windy conditions.

The O/U is 7-0 in Buffalo’s last seven games as an underdog, including 5-0 in its last five as a road dog.

Plus, the O/U is 4-0 in New England’s last four home games.

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