The San Francisco 49ers (2-0) and Houston Texans (2-0) wrap up their preseason schedule Thursday. Kickoff from NRG Stadium is scheduled for 8:15 p.m. ET (Prime Video). Below, we analyze Tipico Sportsbook‘s lines around the 49ers vs. Texans odds, and make our best NFL picks, predictions and bets.
The 49ers hit the road for the 2nd straight preseason game, and try to wrap up the exhibition campaign with a perfect record. San Francisco beat Green Bay 28-21 at home in Week 1 and won 17-7 at Minnesota in Week 2, covering both times.
Coach Kyle Shanahan confirmed this week that the 49ers will play their starters in the preseason finale.
The Texans topped the New Orleans Saints 17-13 in Week 1 and beat the defending Super Bowl champion Los Angeles Rams 24-20 on the road in Week 2. They also have covered both preseason games.
Despite the solid record, QB Davis Mills and the Texans offense haven’t been terribly impressive. The key to success has been defense, with the Houston pass rush recording 11 sacks and 16 total pressures.
49ers at Texans odds
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 1:10 p.m. ET.
- Money line (ML): 49ers -190 (bet $190 to win $100) | Texans +155 (bet $100 to win $155)
- Against the spread (ATS): 49ers -3.5 (-103) | Texans +3.5 (-117)
- Over/Under (O/U): 41.5 (O: -108 | U: -112)
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49ers at Texans picks and predictions
Prediction
49ers 23, Texans 17
Money line
The 49ers (-190) might be a tempting play straight up rather than fiddling around with the points, but it’s risky betting on a road team, especially in a preseason game which is essentially a coin-flip game. While Shanahan confirmed the starters will play, he didn’t say how long.
PASS.
Against the spread
The 49ERS -3.5 (-103) are a much better play laying the points, although 3 and a hook on the road in the preseason is still a rather unsavory number. Still, Mills and the Texans +3.5 (-117) offense has been rather mediocre, and the 49ers will be leaning on the starters at least for a handful of drives.
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Over/Under
The UNDER 41.5 (-112) is the best bet on the board.
The Houston offense has totaled 41 points through 2 preseason games, and the defense has been surprisingly effective with plenty of pressure.
The San Francisco offense wasn’t great last week in a 17-7 win, although it was a mixture of young QBs Brock Purdy and Nate Sudfeld. QB Trey Lance should play, helping the 49ers to more points. But still, this one should be a game with a total in the 30s.
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