San Francisco Giants at Toronto Blue Jays odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Toronto Blue Jays odds and lines, with expert MLB picks, predictions and best bets.

The San Francisco Giants (45-34) and the Toronto Blue Jays (43-37) play the middle contest of a 3-game interleague series Wednesday at Rogers Centre. First pitch is scheduled for 7:07 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Giants vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0 after Tuesday’s 3-0 road victory

The Giants improved to 10-11 in interleague play with Tuesday’s shutout win. Meanwhile, the Blue Jays slipped to 14-7 vs. NL but still have the best interleague winning percentage in the AL.

San Francisco has won 3 of the past 4 games overall. The shutout Tuesday was its 2nd in the past 10 games, and 7th overall this season. The Giants are 18-5 in the past 23 games on the road.

Toronto was blanked Tuesday for the 2nd time in the past 7 games — the only times it has been shut out this season, with both occasions in interleague contests. The Jays are just 5-16 in the past 21 games against NL West teams.

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Giants at Blue Jays projected starters

RHP Logan Webb vs. TBD

Webb (7-6, 3.16 ERA) makes his 17th start. He has a 1.10 WHIP, 1.8 BB/9 and 8.6 K/9 across 105 1/3 IP.

  • Last start: Win, 7 IP, 4 R (3 ER), 5 H, 2 BB, 5 K in an 8-5 home win vs. the Arizona Diamondbacks Friday
  • 2023 road splits: 4-3, 3.84 ERA (58 2/3 IP, 25 ER – 7 HR) with a .252 opponent batting average (OBA) in 9 starts

The Blue Jays are expected to use an opener and have a bullpen game. No starting pitcher was listed at the time of publishing.

Giants at Blue Jays odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:28 a.m. ET.

  • Moneyline (ML): Giants +102 (bet $100 to win $102) | Blue Jays -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants -1.5 (+188) | Blue Jays +1.5 (-230)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Giants at Blue Jays picks and predictions

Prediction

Giants 6, Blue Jays 3

Moneyline

The GIANTS (+102) are worth a look at plus money. Webb has actually been pretty solid on the road, recording 55 K across 58 2/3 IP.

Meanwhile, the Blue Jays will be going with a bullpen game as they are still recovering from having to banish the struggling RHP Alek Manoah to the minors. No one has stepped up, and he is nowhere near returning to form at the lower levels. Toronto’s bullpen is fairly middling, posting a 3.87 ERA which ranks 10th in the AL.

Run line/Against the spread

The GIANTS -1.5 (+195) are worth using on the run line for a chance to nearly double up. San Francisco is 2-1 in the past 3 games as a favorite, covering the run line in each outing.

Meanwhile, the Blue Jays are 1-3 in the past 4 games as underdogs and failed to cover on the run line in all 3 of those setbacks.

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Over/Under

The OVER 8.5 (-105) is a slight lean.

The Over has cashed at a 5-2-1 clip for the Blue Jays in the past 8 games. And again, the Blue Jays bullpen has struggled, and this will be a bullpen game for the Jays.

The Over is 9-4 in the Giants’ last 13 games while going 5-1 across the past 6 contests on the road. The Over is also 6-2 in the past 8 games for San Francisco against opponents with a winning overall record.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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