Washington Commanders at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s Washington Commanders at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The Washington Commanders (2-1) are on the road for the 2nd week in a row and face the Arizona Cardinals (1-2) in Week 4. Kickoff from State Farm Stadium is at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Commanders vs. Cardinals odds, and make our expert NFL picks and predictions.

The Commanders are coming off 2 consecutive wins and rookie QB Jayden Daniels is the reigning NFC Offensive Player of the Week after leading Washington to an upset 38-33 road win over the Cincinnati Bengals on Monday night as 7.5-point underdogs. The Over (46) cashed in.

The Cardinals are coming off a 20-13 loss to the Detroit Lions in Week 3, failing to cover the 3-point spread as home underdogs. The Under (51) cashed in.

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Commanders at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 12:21 a.m. ET.

  • Moneyline (ML): Commanders +150 (bet $100 to win $150) | Cardinals -185 (bet $185 to win $100)
  • Against the spread (ATS): Commanders +3.5 (-115) | Cardinals -3.5 (-105)
  • Over/Under (O/U): 49 (O: -110 | U: -110)

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Commanders at Cardinals key injuries

Commanders

  • WR Jamison Crowder (calf) out
  • RB Austin Ekeler (concussion) out
  • DE Clelin Ferrell (knee) out

Cardinals

  • OL Kelvin Beachum (hamstring) questionable
  • TE Trey McBride (concussion) out
  • DL Khyiris Tonga (knee) out

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Commanders at Cardinals picks and predictions

Prediction

Cardinals 34, Commanders 30

Moneyline

The Commanders are humming offensively, as they have neither punted nor turned the ball over in their last 2 games, scoring on 13 drives and running out the clock on 3 others.

But they have been bad defensively. They are 31st in passing yards allowed per play (7.7) and 30th in rushing yards allowed per play (5.1). The Cardinals showed against the LA Rams in Week 2 what they can do when they can move the ball.

Washington won’t be able to stop the Cardinals, so they will have to keep up, and Arizona will get a stop or 2. Arizona held Detroit scoreless in the 2nd half of last week’s loss.

But the moneyline at -185 for the Cardinals isn’t a good bet, so go with the spread.

PASS.

Against the spread

The Cardinals are 2-1 ATS this season. Considering Washington’s defense, this could be a 1-score game if Washington can continue to protect the football (they have no turnovers in 3 games), but that is nearly impossible to do with a rookie QB for 4 consecutive games, so this is very possible an Arizona blowout.

BET CARDINALS -3.5 (-115).

Over/Under

The Cardinals have scored 28 or more twice and the Over has hit in 2 of the Cardinals’ games.

The Commanders have allowed at least 3 TDs in every game this season and over 30 points in 2 of 3 games.

BET OVER 49 (-110).

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