St. Louis Cardinals at Washington Nationals odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Washington Nationals odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (31-43) are set to play the 3rd game of a 4-game series against the Washington Nationals (27-45) Wednesday at Nationals Park. First pitch is scheduled for 4:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Nationals odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-0

In Tuesday’s 9-3 win over the Nationals, the Cardinals got 3-hit outings from C Willson Contreras and 2B Brendan Donovan. St. Louis has now won 4 consecutive games, and all of the wins have been on the road.

The Nationals have now lost 5 straight games after Tuesday’s 6-run defeat. Washington is 19 1/2 games back of 1st place in the NL East, and it is stymied with the worst record in the NL.

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Cardinals at Nationals projected starters

RHP Miles Mikolas vs. RHP Trevor Williams

Mikolas (4-4, 4.36 ERA) makes his 16th start. He has a 1.36 WHIP, 1.9 BB/9 and 6.5 K/9 through 86 2/3 IP.

  • Has allowed a combined 11 ER on 15 H with 3 BB and 3 K in 12 IP in his last 2 starts
  • Last 5 starts vs. Nationals: 3-1, 3.86 ERA, 1.25 WHIP, 18 K in 32 2/3 IP

Williams (3-4, 4.50 ERA) makes his 15th start. He has a 1.41 WHIP, 3.1 BB/9 and 6.9 K/9 through 70 IP.

  • Has given up 3 ER or more in 5 of his last 8 starts
  • Last 5 starts vs. Cardinals: 0-2, 5.32 ERA, 1.45 WHIP, 22 K in 22 IP

Cardinals at Nationals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:45 a.m. ET.

  • Moneyline (ML): Cardinals -160 (bet $160 to win $100) | Nationals +135 (bet $100 to win $135)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+100) | Nationals +1.5 (-120)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Cardinals at Nationals picks and predictions

Prediction

Cardinals 6, Nationals 4

Moneyline

With St. Louis being the better team in recent games, I’ll side with the CARDINALS (-160) on the road to extend their winning streak. The Cardinals are 4-1 in the last 5 road meetings and the last 5 meetings overall.

Run line/Against the spread

CARDINALS -1.5 (+100) is how I’d bet on the run line with how St. Louis has performed on its road trip. Mikolas hasn’t been reliable for the Cardinals, but he shouldn’t have too much trouble with a Nationals lineup that doesn’t possess much power.

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Over/Under

OVER 9 (-105) has solid value with the Cardinals having success against right-handed pitching. Since the start of June, St. Louis has the 5th-best wRC+ (122) and the 3rd-best ISO (.220) against right-handed hurlers.

The Over is also 6-0 in the Cardinals’ last 6 games following a win and is 4-0 in the last 4 meetings overall.

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