Arizona Diamondbacks at St. Louis Cardinals odds, picks and predictions

Analyzing Thursday’s Arizona Diamondbacks at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (8-11) and St. Louis Cardinals (10-7) clash in a series opener at Busch Stadium Thursday. First pitch is scheduled for 7:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Cardinals odds with MLB picks and predictions.

Season series: First meeting of 2022. St. Louis went 6-1 against Arizona last year.

Arizona arrives in St. Louis after acquitting itself well in a tough 6-game home stand against the New York Mets and Los Angeles Dodgers. The D-backs went 3-3 over the half-dozen games and are 5-3 across their last 8.

The Cardinals snapped a 3-game losing skid with a 10-5 home win over the New York Mets Wednesday. The 10 runs were a welcome change for a Redbirds club that had averaged just 2.60 runs per game over its previous 10 contests. Over that stretch, St. Louis logged a paltry .546 OPS.

RHP Humberto Castellanos vs. RHP Dakota Hudson

Castellanos (1-0, 3.00 ERA) has notched a 1.25 WHIP, 3.8 BB/9 and 6.0 K/9 through 12 IP over 4 games (2 starts).

  • Allowed just 2 runs in 9 IP as a starter
  • Logged a 4.93 ERA in 45 2/3 IP last season

Hudson (1-1, 3.95 ERA) makes his fourth start. He has a 1.17 WHIP, 4.0 BB/9 and 6.6 K/9 through 13 2/3 IP.

  • Held Cincinnati Reds scoreless in a 6 2/3 innings Saturday in last start
  • Appeared in just 13 games (2.93 ERA, 1.03 WHIP in 61 1/3 IP) since having Tommy John surgery in 2020

Diamondbacks at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 2:40 p.m. ET.

  • Money line: Diamondbacks +145 (bet $100 to win $145) | Cardinals -180 (bet $180 to win $100)
  • Against the spread (ATS): Diamondbacks +1.5 (-140) | Cardinals -1.5 (+115)
  • Over/Under (O/U): 7.5 (O: -105 | U: -120)

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Diamondbacks at Cardinals picks and predictions

Prediction

Cardinals 5, Diamondbacks 4

Money line

This wager fits as a play fading a Cardinal bullpen getting by on a .250 batting average on balls in play and a St. Louis offense leveraging a .359 BABIP in high-leverage situations.

The visiting Diamondbacks have played well lately. Their bullpen is not in great shape heading into Thursday’s game, but the tag here makes DIAMONDBACKS (+145) worth a shot even if its a 55-60% likelihood the Cards win the game.

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Run line/Against the spread

PASS. The plus money is worth the shot in the money-line play.

Over/Under

There is some growth room in the Arizona batting and run-scoring numbers, and much of the pitching analysis on both sides is fade-worthy. With the low total, BACK THE OVER 7.5 (-105).

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