Detroit Lions at Cleveland Browns odds, picks and prediction

Analyzing Sunday’s Detroit Lions at Cleveland Browns odds and lines, with expert NFL picks, predictions and best bets.

The Detroit Lions (0-8-1) visit the Cleveland Browns (5-5) Sunday for a Week 11 game at FirstEnergy Stadium. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Lions vs. Browns odds and lines, and make our best NFL picks, predictions and bets.

The Lions scratched out a 16-16 tie in Pittsburgh last week. The 16 points allowed was a season-best for the Detroit defense. Detroit is a respectable 5-4 ATS overall this season.

The Browns were paddled in New England by a 45-7 count last weekend, and Cleveland is now 2-4 SU/ATS across its last six games. The Over cashed for the second straight week and is 4-2 over the previous six outings.

Also see: All Week 11 odds and lines

Lions at Browns odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 9 a.m. ET.

  • Money line: Lions +400 (bet $100 to win $400) | Browns -550 (bet $550 to win $100)
  • Against the spread (ATS): Lions +12.5 (-108) | Browns -12.5 (-112)
  • Over/Under (O/U): 42.5 (O: -112 | U: -108)

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Lions at Browns key injuries

Lions

  • RB Jermar Jefferson (knee, ankle) out
  • QB Jared Goff (oblique) doubtful
  • RB Jamaal Williams (thigh) questionable
  • LB Trey Flowers (knee) out

Browns

  • CB Troy Hill (neck) out
  • WR Donovan Peoples-Jones (groin) questionable
  • WR Anthony Schwartz (concussion) out

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Lions at Browns odds, lines, predictions and picks

Prediction

Browns 29, Lions 13

Money line

Browns (-550) will cost you five and a half times your potential return, but Cleveland is just too risky to play at those odds even at home against a winless Lions team.

AVOID.

Against the spread

The BROWNS -12.5 (-112) haven’t really played well enough to be favored by double digits, but the Lions have issues. QB Tim Boyle is expected to make his first NFL start in place of the injured QB Jared Goff, and that isn’t likely to end very well at all for the visitors.

Over/Under

The UNDER 42.5 (-108) is the lean in this one. The Cleveland offense gets RB Nick Chubb back from the reserve/COVID list, and it’ll likely lean on the back for most of the backfield work with RB D’Ernest Johnson also figuring in. Cleveland loves to run, run and then run some more, which also runs the clock. The Lions have a first-time NFL starter under center. All signs point to an Under result here.

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