Los Angeles Rams road favorites vs. San Francisco 49ers in Week 6

The 4-1 Los Angeles Rams are Week 6 betting road favorites against the struggling San Francisco 49ers on Sunday Night Football.

The Los Angeles Rams (4-1) are back on the road in Week 6, once again as the betting favorites. They’ll take on the San Francisco 49ers (2-3) at Levi’s Stadium on Sunday Night Football at 8:20 p.m. ET. Below, we take a look at the early Week 6 betting odds and lines at BetMGM Sportsbook.

The Rams are coming off a dominant 30-10 win over the Washington Football Team, limiting Ron Rivera’s squad to only 108 total yards. QB Jared Goff and the Rams offense are playing well, too, totaling 429 yards of total offense in Week 5 en route to their second straight win.

The 49ers are trending in the opposite direction, getting blown out 43-17 by the Miami Dolphins at home in Week 5. It was San Francisco’s second straight loss, dropping its record to 2-3. QB Jimmy Garoppolo was benched against Miami, so it remains to be seen who head coach Kyle Shanahan will go with as his starting quarterback against the Rams.

Rams at 49ers betting odds, spread and line

Odds via BetMGM; last updated Tuesday at 10:30 a.m. ET.

  • Money line: Rams -189 (bet $189 to win $100) / 49ers +160 (bet $100 to win $160) | Bet now
  • Against the spread: Rams -3.5, -110 (bet $110 to win $100) / 49ers +3.5, -110 (bet $110 to win $100) | Bet now
  • Total: 50.5, Over -110 (bet $110 to win $100) / Under -110 (bet $110 to win $100) | Bet now

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As the favorites, the Rams have an implied win probability of 65.40% on the money line of -189. In order for them to cover the 3.5-point spread, they have to win by at least 4 points against the 49ers.

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The 49ers have an implied win probability of 38.46% against the Rams with the money line of +160. If San Francisco loses by three or fewer points or wins outright, it will cover the 3.5-point spread.

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